Renal interstitial fibrosis: remembrance of things past?

اثر سیمواستاتین بر فیبروز کلیه متعاقب انسداد کامل یکطرفه میزنای در موش صحرایی

Introduction & Objective: Comparative reductase inhibitors, such as simvastatin increase HDL-cholestrol and decrease serum triglyceride and cholesterol. It is widely recognized that statins have organ protective nature and most effective for organ damage progressing. Obstructive uropathy can be used to indicate any obstruction to urinary flow which causes a developing of hydronephrosis, tubul...

Remembrance of Things Past

Crystal-associated nephropathy in patients with brushite nephrolithiasis.

BACKGROUND We have biopsied the renal cortex and papillae of patients who form brushite renal stones asking if this unusual stone type is associated with specific tissue changes. We contrasted these with biopsies of 15 calcium oxalate stone formers, three stone formers with intestinal bypass, and four normal subjects. METHODS We studied all ten brushite stone formers treated with percutaneous...

Induced Autologous Stem Cell Transplantation for Treatment of Rabbit Renal Interstitial Fibrosis

INTRODUCTION Renal interstitial fibrosis (RIF) is a significant cause of end-stage renal failure. The goal of this study was to characterize the distribution of transplanted induced autologous stem cells in a rabbit model of renal interstitial fibrosis and evaluate its therapeutic efficacy for treatment of renal interstitial fibrosis. METHODS A rabbit model of renal interstitial fibrosis was ...

Remembrance of Things Past: Greenhouse Lessons from the Geologic Record

Global climate--like local weather--is ever changing, on all time scales, in response to natural variations. For this reason, projections of global warming, resulting from increasing levels of atmospheric greenhouse gases, need to be set in the context of what has happened in the past. A knowledge of what has changed, and when and where, provides insights into why past changes have occurred. Su...